Pesticides as a possible precursors of N-nitrosamines.

Nitrosamines and Pesticides: a Special Report on the Occurrence of Nitrosamines as Terminal Residues Resulting from Agricultural Use of Certain Pesticides

Nitrosarnine contaminants in certain pesticide formulations, especially dinitroaniline and some acid herbicides, has been firmly established. These contaminants arise from either chemical synthesis, as with the dinitroanilines, or from nitrosation in the product due to nitrite, as with certain halobenzoic acid formulations. The nitrosamines are either simple nitrosodialkylamine compounds or the...

Anion exchange resins as a source of nitrosamines and nitrosamine precursors.

Anion exchange resins are important tools for the removal of harmful anionic contaminants from drinking water, but their use has been linked to the presence of carcinogenic nitrosamines in treated drinking water. In bench-scale batch and column experiments, anion exchange resins from a large, representative group were investigated as sources of the nitrosamines N-nitrosodimethylamine (NDMA), N-...

Increase in human exposure to methylamine precursors of N-nitrosamines after eating fish.

Consumption of fish has been encouraged recently because it may prevent mortality due to heart disease. Fish contains methylamines, which are precursors of N-nitrosamines. Nitrosamines can act as potent carcinogens in a wide variety of animal species, and there is no reason to assume that humans are resistant. Human subjects (n = 5) ingested a diet of known methylamine content for 2 days. On Da...

Winter Counts as Possible Precursors to Writing

Formation and Metabolism of N-Nitrosamines

The formation of nitrosamines and reactions of the first and second phase of their biotransformations were reviewed.